Christina Vasileva grew up in Sofia in a Czech-Bulgarian family. After finishing her studies at the Conservatory Ljubomir Pipkov Sofia, she studied with Michael Tomaschov belcanto-singing. - She launched her international career with the international singing competition Antonín Dvorák. She became a member of the F.X. Salda Theatre, Liberec. There she sang Rusalka, Violetta (La Traviata), Tatiana (Eugene Onegin), Desdemona (Otello), Cio-Cio-San (Madama Butterfly), Antonia (The Tales of Hoffmann), Micaela (Carmen), Fiordiligi (Cosi fan tutte ), Nedda (I Pagliacci), Leonara (Il Travatore), Manon Lescaut (Manon Lescaut). In 2002 she sang Rusalka at the National Theatre in Prague and one year later in Brno. She also worked with the opera houses in Ústí nad Labem and Pilsen, where she sung Violetta and Cio-Cio-San.

Christina Vasileva has also performed at opera houses in Europe and overseas: Rusalka at the National Theatre in Zagreb (1996), Cio-Cio-San in the Eutiner Festival in Remscheid and Solingen with the Hamburg Philharmonic under Hilary Griffiths (1999 and 2000) , Norma at the Teatro Puccini in Rhodes (2002) and  Desdemona at the Theater Winterthur (2004). An extraordinary success she had in 2003 as Violetta in Oji Hall in Tokyo. 1998 and 2003 she sang with Peter Dvorsky and the Prague Chamber Philharmonic opera recitals. In 2008, critics have highly praised her performance as Liù (Turandot) in Salzburg under Enrico Dovico.

Christina Vasileva was from 2006 to 2011 a soloist of the Prague State Opera, where she sang Elena (I vespri siciliani), Cho-Cho-San, Mimi (La Bohème), Manon Lescaut, Rusalka, Tosca and Desdemona. In the season 2006/2007 they had a great success with the title role of the opera Hélène by Camille Saint-Saëns as a concert performance.

In the fall of 2008, she was nominated for the Thalia Award with the role of Mimi in La Bohème (Director: Ondřej Havelka).

In March 2011, she was awarded the Thalia Award for the title role in Janáček's Katya Kabanova (directed by Robert Wilson), which she sung in 2010 at the National Theatre in Prague.

This was followed by guest appearances at the Theater Freiburg in the years 2011 to 2013 as Desdemona, Manon, Elsa (Lohengrin), Lisa (Pique Dame). With her Desdemona, directed by Eva-Maria Hockmayr she was nominated for Vocalist of the Year by the international opera magazine „Opernwelt“.

The concert performance of Zandonai "Francesca da Rimini" in July 2013, in which Christina Vasileva sang the title role, was a great success and next to the radio broadcast by „Deutschlandfunk Kultur“ there will be also a CD recording of this concert.

In the season 2013/14 they will sing "I vespri Siciliani" by G. Verdi and Giorgetta "I tabarro" by G. Puccini in Freiburg Elena.